Gases from a comet's tail bestow superhuman powers on the babies born at the moment when it passes through Earth's atmosphere. We follow the stories of five children: Jamie from Ghana, Sarimah from Malaysia, Joelle from New Zealand, and the twins Liam and Kwaku from Ireland. As they grow older, they discover their talents - and their enemies.
At seventeen, they discover each other through hints dropped in an online forum - but they aren't the only ones watching. Mobsters based in Chicago hold another group of Comet Born kids underground, experimenting on them in search of the secret to their powers - while their families are held to ransom to ensure their cooperation.
But a friend on the inside takes up their cause in secret, and the free Comet Born go undercover in that most international of cities: Jerusalem.